Record Display for the EPA National Library Catalog

RECORD NUMBER: 2 OF 2

Main Title

Measurement of Blood Cholinesterase Activity in Laboratory Animals Utilizing Dimethylbutyl Acetate as a Substrate.

Author

Cranmer, Morris F. ; Peoples., Anita J. ;

CORP Author

Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.

Year Published

1973

Report Number

found in PB-280 889

Stock Number

PB-280 902, found in PB-280 889

Additional Subjects

Cholinesterase ; Pesticides ; Toxicology ; Enzymes ; Acetic acid ; Activity ; Laboratory animals ; Experimental data ; Monkeys ; Dogs ; Rats ; Mice ; Rabbits ; Cholinesterase inhibitors ; In vivo analysis ; Substrates ; Blood chemical analysis ; Carbaryl ; Reprints ; Acetic acid/butyl-dimethyl ; Toxic substances ; Parathion

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB-280 902	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

Abstract

Blood cholinesterase activity was measured in the monkey, dog, rat, mouse, and rabbit. The use of the substrate, dimethyl butyl acetate, resulted in expected values for the monkey, dog, and rabbit, but the cholinesterase activity of the rat and mouse was quite elevated. In vivo cholinesterase inhibition resulted in lower values in all animals. Dimethyl butyl acetate was indicated an acceptable substrate for measuring cholinesterase activity except in the mouse and rat, where high levels of non-specific esterases complicated interpretation.

Notes

contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.