| Main Title |
Comparative Stimulation of gamma HCH Metabolism by Pretreatment of Rats with gamma HCH, DDT, and DDT gama HCH. |
| Author |
Chadwick, R. W. ;
Cranmer, M. F. ;
Peoples., A. J. ;
|
| CORP Author |
Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab. |
| Year Published |
1970 |
| Stock Number |
PB-277 608 |
| Additional Subjects |
DDT ;
Pesticides ;
Insecticides ;
Toxicology ;
Metabolism ;
Rats ;
Ingestion(Biology) ;
Toxicity ;
Dosage ;
Laboratory animals ;
Experimental data ;
Chlorine organic compounds ;
Bioassay ;
Cyclohexane/hexachloro ;
Reprints ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-277 608 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1p |
| Abstract |
Pretreatment of rats with gamma HCH, DDT, and DDT + gamma HCH accelerates the metabolism of gamma HCH. A single oral dose of 14C - gamma HCH was administered to all animals after a 2-week pretreatment period. The treated rats excreted significantly more radioactivity and stored significantly less 14C - gamma HCH than the control animals. Results of this study suggest that the mechanism by which gamma HCH induces its own degradation differs from the mechanism through which DDT stimulates gamma HCH metabolism. |
