||Animal Models for Assessing the Neurobehavioral Impact of Airborne Pollutants.
MacPhail, R. C. ;
Peele, D. B. ;
||Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. ;Northrop Services, Inc., Research Triangle Park, NC.
Animal disease models ;
Air pollution effects(Animals) ;
Animal behavior ;
Indoor air pollution ;
Carbon monoxide ;
Acetic acid ;
Avoidance learning ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
There has been a long-standing tradition of experimentation on laboratory animals and the behavioral effects of airborne pollutants. These studies provide a scientific basis for investigating many of the pressing issues on indoor-air pollution. Several different procedures are reviewed, along with representative data taken from the literature. Models are already available for quantitatively assessing the noxious properties of airborne chemicals. A number of physiological responses pertinent to the sick building syndrome have been shown to be produced by conditioning in laboratory animals. The possibility is suggested that similar conditioning may take place in affected humans.