||Intratracheal Infection with 'L. pneumophila' Subtypes.
Plouffe, J. F. ;
Para, M. F. ;
Fuller, K. A. ;
||Ohio State Univ., Columbus. Div. of Infectious Diseases.;Health Effects Research Lab., Research Triangle Park, NC.
||EPA-R-812704 ;EPA-R-811023; EPA/600/J-86/252;
Respiratory injections ;
Guinea pigs ;
Laboratory animals ;
Potable water ;
Legionnaires disease ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
Two strains of Legionella pneumophila serogroup 1 (UH1 and RH1) were injected intratracheally into guinea pigs. There were no differences in infectivity or mortality, but there was evidence of disseminated infections in more guinea pigs infected with the UH1 strain. Guinea pigs that received sublethal inocula were then rechallenged intratracheally and had a lower mortality rate than did previously uninfected controls. (Copyright (c) 1986 Teviot-Kimpton Publications.)