Main Title |
Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy / [electronic resource] : |
Type |
EBOOK |
Author |
Pandolfi, Pier Paolo.
|
Other Authors |
|
Publisher |
Springer Berlin Heidelberg, |
Year Published |
2007 |
Call Number |
RC261-271 |
ISBN |
9783540345947 |
Subjects |
Medicine ;
Oncology
|
Internet Access |
|
Collation |
VII, 273 p. 16 illus. online resource. |
Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
Contents Notes |
APL as a Paradigm in Biomedical Research: A Journey Toward the Cure -- Mouse Models of Acute Promyelocytic Leukemia -- The PLZF Gene of t(11;17)-Associated APL -- SUMO, the Three Rs and Cancer -- Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia -- The Theory of APL Revisited -- Treatment of Acute Promyelocytic Leukemia by Retinoids -- Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological -- Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia -- Histone Deacetylase Inhibitors in APL and Beyond -- Monoclonal Antibody Therapy of APL -- Targeting APL Fusion Proteins by Peptide Interference -- The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia. (will follow) |