| Main Title |
Carcinogenicity assessment of aldrin and dieldrin. |
| Author |
Cavender, F. L. ;
Cook, B. T. ;
Page, N. P. ;
Cogliano, V. J. ;
Hajjar, N.
|
| CORP Author |
United States. Environmental Protection Agency. Office of Health and Environmental Assessment. |
| Publisher |
Carcinogen Assessment Group, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, |
| Year Published |
1987 |
| Report Number |
EPA/600/6-87/006 |
| Stock Number |
PB88-139951 |
| OCLC Number |
17196864 |
| Subjects |
Dieldrin--Carcinogenicity ;
Dieldrin--Toxicology ;
Insecticides--Toxicology ;
Pesticides--Toxicology
|
| Additional Subjects |
Carcinogens ;
Carcinogenicity testing ;
Pesticides ;
Insecticides ;
Toxicology ;
Epidemiology ;
Exposure ;
Bioassay ;
Laboratory animals ;
Carcinogenesis ;
Aldrin ;
Dieldrin
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EHAM |
EPA/600/6-87/006 |
|
Region 1 Library/Boston,MA |
05/25/2016 |
| EJED |
EPA 600/6-87-006 |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
| EKBD |
EPA-600/6-87-006 |
|
Research Triangle Park Library/RTP, NC |
01/01/1988 |
| EKCD |
EPA/600/6-87/006 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
07/25/2018 |
| ELBD ARCHIVE |
EPA 600-6-87-006 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
| ERAD |
EPA 600/6-87-006 |
|
Region 9 Library/San Francisco,CA |
02/18/1994 |
| ESAD |
EPA 600-6-87-006 |
|
Region 10 Library/Seattle,WA |
01/02/1998 |
| NTIS |
PB88-139951 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1 volume (various pagings) : illustrations ; 28 cm |
| Abstract |
Evidence pertaining to the carcinogenicity of aldrin/dieldrin is reviewed and evaluated. The report covers studies completed before 1985. Case reports and epidemiologic studies of pesticide applicators and pesticide manufacturing workers are reviewed, but because of methodologic limitations, these studies established neither a positive nor a negative association between cancer and aldrin/dieldrin exposure. A number of independent studies of laboratory animals, however, demonstrated that aldrin/dieldrin cause liver cancer in mice and rats. Based on the accumulated evidence, aldrin/dieldrin are classified as probable human carcinogens, Group B2, using EPA's Guidelines for Carcinogen Risk Assessment. The carcinogenic potency of aldrin/dieldrin is estimated by fitting mathematical models to the laboratory animal data. These estimates indicate that aldrin/dieldrin are rather potent carcinogens, ranking in the second quartile of potential carcinogens evaluated by EPA's Carcinogen Assessment Group. |
| Notes |
"Drafted by Dynamac Corporation, Rockville, Maryland, under EPA contract number 68-02-4131"--Page xiii. Distributed to depository libraries in microfiche. "August 1987." Includes bibliographical references (pages 6-1-6-10). "EPA/600/6-87/006." |
