| Main Title |
'Neanthes arenaceodentata' (Polychaeta: Annelida), a Proposed Cytogenetic Model for Marine Genetic Toxicology. |
| Author |
Pesch, Gerald G. ;
Pesch, Carol E. ;
|
| CORP Author |
Environmental Research Lab., Narragansett, RI. |
| Year Published |
1981 |
| Report Number |
EPA-600/J-80-233 ;ERLN-J132; |
| Stock Number |
PB81-184715 |
| Additional Subjects |
Toxicology ;
Annelida ;
Chromosomes ;
Models ;
In vivo analysis ;
Concentration(Composition) ;
Reprints ;
Neanthes arenaceodentata ;
Sister chromatid exchange ;
Mitomycin ;
Cytogenetics
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB81-184715 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
4p |
| Abstract |
Genetic toxicants are present in polluted marine environments and may represent a long-term threat to populations of marine organisms. This paper presents details of an in vivo application of sister chromatid exchange (SCE) analysis to a marine polychaete worm Neanthes arenaceodentata. This species exhibits a dose response to mitomycin C (MMC) at concentrations comparable to those eliciting responses in in vivo mammalian systems. A dose of 5 x 10 to the minus 7th power mol/L MMC increased the rate of SCE from a baseline frequency of 0.14/chromosome to 0.5/chromosome. The chromosomes of N. arenaceodentata may provide a useful model for identifying and studying the effects of genetic toxicants in marine environments. |
