Record Display for the EPA National Library Catalog


Main Title Effects of Age and Body Lead Burden on CNS Function in Young Children. I. Slow Cortical Potentials.
Author Otto, D. A. ; Benignus, V. A. ; Muller, K. E. ; Barton, C. N. ;
CORP Author North Carolina Univ. at Chapel Hill.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-68-02-1702; EPA-600/J-80-172;
Stock Number PB82-247222
Additional Subjects Age ; Lead(Metal) ; Children ; Reprints ; Cortical potentials
Library Call Number Additional Info Location Last
NTIS  PB82-247222 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
The effects of body Pb burden on slow cortical potentials were studied in 63 children aged 13-75 months. Slow wave (SW) voltage during sensory conditioning varied as a linear function of blood lead (PbB) level. The slope of this fuction, moreover, changed systematically with age. For children under 5 years of age, SW voltage tended to be positive at low PbBs and to be negative above 30 micrograms/d1. For children over 5 years of age, SW voltage tended to be negative at low PbBs and to be less negative (or positive) above 30 micrograms/d1. These results provide evidence of altered CNS function at the lowest Pb effect level ever reported.