| Main Title |
Eye irritation testing : an assessment of methods and guidelines for testing materials for eye irritancy / |
| Author |
Falahee, K. J. ;
Rose, C. S. ;
Olin, S. S. ;
Seifried, H. E.
|
| CORP Author |
United States. Environmental Protection Agency. Office of Pesticides and Toxic Substances. |
| Publisher |
Distributed by National Technical Information Service, |
| Year Published |
1981 |
| Report Number |
EPA-560/11/82-001; EPA-68-01-6176 |
| Stock Number |
PB82-225764 |
| OCLC Number |
09750254 |
| Subjects |
Toxicology--Methods ;
Toxicology, Experimental
|
| Additional Subjects |
Toxicology--Methods ;
Toxicology, experimental ;
Eye injuries ;
Assessments ;
Rabbits ;
Bioassay ;
Laboratory animals ;
In vivo analysis ;
In vitro analysis ;
Tests ;
Guidelines ;
Methodology ;
Irritants ;
Toxic substances ;
Draize method ;
Tier testing
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD ARCHIVE |
EPA 560-11-82-001 |
|
Headquarters Library/Washington,DC |
05/04/2011 |
| EJED |
EPA 560-11-82-001 |
|
OCSPP Chemical Library/Washington,DC |
10/08/2004 |
| ELBD RPS |
EPA 560-11-82-001 |
repository copy |
AWBERC Library/Cincinnati,OH |
03/21/2016 |
| ELBD |
EPA 560-11-82-001 |
|
AWBERC Library/Cincinnati,OH |
03/23/2016 |
| NTIS |
PB82-225764 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
xii, 83 pages : illustrations ; 28 cm |
| Abstract |
The ocular safety of materials is determined primarily by observing the irritation produced by test agents instilled directly into the rabbit eye. The object of this study was to review the scientific basis for published guidelines, particularly those recently developed by the Organization for Economic Cooperation and Development (OECD) and the Interagency Regulatory Liaison Group (IRLG). These guidelines are essentially the same and recommend instillation of 0.1 ml material into the rabbit eye with observation for at least 72 hr. |
| Notes |
Contract no.: 68-01-6176. Report no.: EPA 560/11-82-001. Project officer: Charles Auer. Technical advisors: Norbert P. Page, Daljit Sawhney. Prepared by Tracor Jitco, Inc. Includes bibliographical references (pages 63-72). |
