Includes index.

Basic concepts in immunology -- Innate immunity -- Antigen recognition by b-cell and t-cell receptors -- The generation of lymphocyte antigen receptors -- Antigen presentation to t lymphocytes -- Signaling through immune system receptors -- The development and survival of lymphocytes -- T cell-mediated immunity -- The humoral immune response -- Adaptive immunity to infection -- The mucosal immune system -- The immune system in health and disease -- Failures of host defense mechanism -- Allergy and hypersensitivity -- Autoimmunity and transplantation -- Manipulation of the immune response -- Evolution of the immune system. This authoritative textbook summarises the basic immunological concepts, looks at the main aspects of adaptive immunity, then integrates all the preceding material at the level of the complete organism in both health and disease.