Record Display for the EPA National Library Catalog


Main Title Biological transfer of plutonium via in vivo labeled goat's milk /
Author Sutton, William W. ; Mullen, Anita A. ; Lloyd, Stephen R. ; Mosley., Robert E.
Other Authors
Author Title of a Work
Sutton, William W.
CORP Author Environmental Monitoring and Support Lab., Las Vegas, Nev. Monitoring Systems Research and Development Div.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Monitoring and Support Laboratory, Monitoring Systems Research and Development Division ; For sale by the National Technical Information Service,
Year Published 1976
Report Number EPA-600/3-76-025
Stock Number PB-252 244
OCLC Number 02326259
ISBN pbk.
Subjects Goat milk. ; Plutonium. ; Goat's milk
Additional Subjects Plutonium ; Food ; Milk ; Food chains ; Transport properties ; Metabolism ; Ingestion(Biology) ; Plutonium 238 ; Plutonium 239 ; In vivo analysis ; In vitro analysis ; Labeled substances ; Gastrointestinal system ; Absorption(Biology) ; Rats ; Goats ; Radiation dosage ; Experimental data
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-3-76-025 Headquarters Library/Washington,DC 12/07/2011
EJBD  EPA 600/3-76-025 Headquarters Library/Washington,DC 03/11/2014
EKBD  EPA-600/3-76-025 Research Triangle Park Library/RTP, NC 07/28/2000
ESAD  EPA 600-3-76-025 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB-252 244 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation vii, 17 p. : ill., graphs ; 28 cm.
The long physical and biological half-life and high relative toxicity have dictated that considerable effort be devoted to quantifying plutonium transport through the various trophic levels. Despite the fact that biological transport of plutonium has been studied for many years, quantitative values for its transfer to milk, and its subsequent uptake by suckling animals have not been established. Three lactating goats were given intravenous injections of citrate-buffered plutonium nitrate at a rate of 75 microcuries per animal per day for three consecutive days. In all three goats approximately one percent of the total plutonium dose was transferred to the milk by the fifth post-treatment day. Plutonium retained by the tissues was deposited primarily in the liver and bone. In vitro plutonium-labeled milk was also fed to groups of rats and juvenile goats. Tissue concentrations of plutonium from juvenile goats which had received either in vivo or in vitro labeled milk were somewhat variable. Due possibly to this, within group variability and the small number of animals per group (two) there were no clearly discernible differences between treatments. The only comparison point to show a consistent trend was the observation that, as expected, juvenile rats retained more of the ingested dose than the adult animals.
Includes bibliographical references (p. 17). Item 431-I-11.