Record Display for the EPA National Library Catalog


Main Title LEAD : environmental sources and red cell toxicity in urban children /
Author Angle, Carol R. ; McIntire., Matilda S.
Other Authors
Author Title of a Work
McIntire, Matilda S.
CORP Author Nebraska Univ., Omaha. College of Medicine.;National Environmental Research Center, Research Triangle Park, N.C. Human Studies Lab.
Publisher U.S. Environmental Protection Agency,
Year Published 1975
Report Number EPA/650-1-75-003; EPA-R-802043; PB249061
Stock Number PB-249 061
OCLC Number 02167687
Subjects Lead--City children ; Lead--Toxicology ; Environmental health--City children
Additional Subjects Lead poisoning ; Toxicity ; Nebraska ; Urban areas ; Children ; Exposure ; Toxic diseases ; Recommendations ; Design ; Objectives ; Metabolism ; Erythrocytes ; Blood cells ; Quantitative analysis ; Enzymes ; Iron deficiency anemia ; Soil analysis ; Water analysis ; Air pollution ; Tables(Data) ; Environmental health ; Air pollution effects(Humans) ; Omaha(Nebraska) ; Body burdens
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 650-1-75-003 Headquarters Library/Washington,DC 07/11/2016
EJBD  EPA 650-1-75-003 Headquarters Library/Washington,DC 10/23/2018
EKBD  EPA/650-1-75-003 Research Triangle Park Library/RTP, NC 04/02/2019
ERAD  EPA 650/1-75-003 Region 9 Library/San Francisco,CA 04/10/2019
ESAD  EPA 650-1-75-003 Region 10 Library/Seattle,WA 09/17/2004
NTIS  PB-249 061 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation x, 80 pages : illustrations, maps ; 28 cm.
A comprehensive environmental study was carried out for correlation of lead in multiple sources with the increased blood lead of urban children. In the three age groups, 2-5, 10-12, and 14-18 years, urban children had higher blood leads than their suburban counterparts, although the difference decreased with age. The increased blood lead correlated with increased lead in the urban dustfall, yard soil and boot tray lead. There was no significant urban-suburban difference in air lead, housedust lead, available paint chips or lead in milk and water. Lead in yard dirt and blood lead both correlated with residential proximity to traffic. Although all blood lead were below 40 micrograms/dustfall lead, there was a significant linear decrease in red cell (rbc) membrane Na/K ATPase as blood lead increased; children with a blood lead above 20 micrograms/dustfall lead had decreased activity of rbc glutathione and increased rbc G-6-PD and 6-PGD. The increase in the latter two enzymes supports decreased rbc survival at the level of lead exposure of urban children.
Prepared for United States Environmental Protection Agency, Office of Research and Development. Grant no. 802043; program element no. AA005. Includes bibliographical references (pages 72-78). "June 1975." "EPA/650-1-75-003."