| Main Title |
Multicompartment Kinetic Models for Lead. 1. Bone Diffusion Models for Long-Term Retention. |
| Author |
Marcus, A. H. ;
|
| CORP Author |
Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1985 |
| Report Number |
EPA/600/J-85/424; |
| Stock Number |
PB86-220399 |
| Additional Subjects |
Lead(Metal) ;
Bone ;
Models ;
Blood plasma ;
Dogs ;
Reprints ;
Kinetic models
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-220399 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
20p |
| Abstract |
The long-term retention of lead in bone poses a number of difficulties for the usual multicompartment models. The use of diffusion models based on exchange of lead between blood in canaliculi and the crystalline bone of the osteon allows a linear compartmental approximation suitable for statistical estimation of kinetic parameters in peripheral compartments. The model is applied to lead retention by beagle dogs. |
