Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Evidence of Migration of Ingested Asbestos into Various Baboon Organs.
Author Patel-Mandlik, Kusum J. ; Millette, James R. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1980
Report Number EPA-600/J-81-192;
Stock Number PB81-212201
Additional Subjects Asbestos ; Toxicology ; Ingestion(Biology) ; Electron microscopy ; Dosage ; Tissues(Biology) ; Electron microscopy ; Dosage ; Tissues(Biology) ; Bioassay ; Pathology ; Reprints ; Baboons ; Toxic substances ; NTISEPAORD
Library Call Number Additional Info Location Last
NTIS  PB81-212201 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
This report presents the results of transmission electron microscopic analysis for asbestos in ten organs of the newborn baboon who was orally administered with chrysotile asbestos. The feeding period consisted of 9 days with a cumulative dose of 3 x 10 to the 13th power chrysotile fibers per kilogram. Analysis of the same ten organs of a control newborn baboon is also included. The test tissues showed higher levels of asbestos than respective control tissues. The highest concentration of chrysotile fibers was found in the kidney cortex followed by lymph nodes, spleen, colon, esophagus, kidney medulla, stomach, and liver. Fiber size distribution of the fibers recovered indicated that the longest fiber was retained in the kidney cortex.