Record Display for the EPA National Library CatalogRECORD NUMBER: 1 OF 45
|Main Title||Acid aerosol deposition in the developing human lung /|
|Author||Martonen, T. B.|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Publisher||U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory ; Reproduced by National Technical Information Service,|
|Additional Subjects||Aerosols ; Lung ; Aging(Biology) ; Hygroscopicity ; Growth ; Children ; Particles ; Reprints ; Sulfuric acid ; Air pollution effects(Humans) ; Toxic substances ; Health hazards|
|Collation||7 pages ; 28 cm|
Computations of aerosol deposition as affected by (i) aerosol hygroscopicity, and (ii) human age, have been done using a validated theoretical model. The behavior of inhaled H2SO4 particles subsequent to water vapor uptake significantly influences their relative spatial distribution patterns within human lungs. These observations must be accounted for in risk assessment protocols since compartments of the lung have distinctive clearance processes and reactions to toxic materials. Calculations also establish that subject age is a critical variable to incorporate into health effects studies. This is of particular importance since children are a potentially sensitive subpopulation of concern related to inhalation exposures to airborne contaminants.
"Published in the Proceedings of the International Aerosol Conference, (Pergamon Press)." "PB90-263211." "EPA/600/D-90/136." Microfiche.