Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Health assessment document for epichlorohydrin /
Author Keneklis, T. ; Bayard, S. ; Anderson, L. ; Sakai, C. ; Lavappa, K. S. ;
CORP Author Environmental Protection Agency, Research Triangle Park, NC. Environmental Criteria and Assessment Office. ;Dynamac Corp., Rockville, MD.
Publisher U.S. Environmental Protection Agency, Office of Research and Development,
Year Published 1983
Report Number EPA/600-8-83-032a
Stock Number PB84-128669
OCLC Number 10320853
Subjects Environmental health. ; Epichlorohydrin--Toxicology. ; Carcinogens.
Additional Subjects Epichlorohydrin ; Environmental surveys ; Toxicity ; Air pollution ; Public health ; Assessments ; Physical properties ; Chemical properties ; Risk ; Carcinogens ; Metabolism ; Reviews ; Transport properties ; Utilization ; Laboratory animals ; Mutagens ; Regulations ; Water pollution ; Air pollution effects(Humans) ; Air pollution effects(Animals) ; Clean air act ; Path of pollutants ; Ecosystems ; Solid wastes
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  RA1242.E74EPA-600 8-83-032F Region 1 Library/Boston,MA 04/29/2016
EJBD ARCHIVE EPA 600-8-83-032A Headquarters Library/Washington,DC 07/03/2013
EJBD  EPA 600-8-83-032A c.1 Headquarters Library/Washington,DC 07/03/2013
ESAD  EPA 600-8-83-032a Region 10 Library/Seattle,WA 09/06/2005
NTIS  PB84-128669 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Edition External review draft.
Collation xv, [210] pages : illustrations ; 28 cm
This document summarizes current scientific information regarding the health and environmental effects of epichlorohydrin. The observed effects, as presented herein, constitute the health basis from which the U.S. Environmental Protection Agency will make a decision whether to list and to regulate epichlorohydrin as a hazardous air pollutant under the Clean Air Act. Specifically, this document discusses the following topics: physical and chemical properties of epichlorohydrin; environmental occurrence; metabolism, toxicology, and climination; and factors most relevant to assessing quantitative health risks.
Dynamac Corporation prepared the chapters on physical and chemical properties, sampling, analysis, and toxicity data. "Do not cite or quote"--Cover. "Noticee, this document is a preliminary draft. It has not been formally released by EPA and should not at this stage be construed to represent Agency policy. It is being circulated for comment on its tecnical accuracy and policy implications." "EPA/600-8-83-032a." October 1983." Includes bibliographical references (pages R-1-R-14).
Contents Notes
3. Background information -- 3.1 Physical and chemical properties -- 3.2 Analytical methodology -- 3.3 Production, use, and releases to the environment -- 3.4 Environmental transport and fate -- 4. Compound distribution and related pharmacokinetics in humans and animals -- 4.1 Routes of exposure and absorption -- 4.2 Distribution -- 4.3 Metabolite identification and pathways -- 4.4 Excretion -- 5. Effects on humans -- 5.1 Epidemiologic studies -- 5.2 Effects on the nervous system -- 5.3 Effects on blood and hematopoietic tissue -- 5.4 Effects on the liver -- 5.5 Effects on the skin -- 5.6 Effects on male fertility -- 6. Animal toxicology -- 6.1 Species sensitivity -- 6.2 Effects on the liver, kidneys, and lungs -- 6.3 Behavorial toxicity and central nervous system effects -- 6.4 Other tissues or organs -- 7. Carcinogenicity, mutagenicity, and reproductive and teratogenic effects -- 8. Synergism and antagonism at the physiological level -- 9. Ecosystem considerations -- 9.1 Effects on microorganisms and plants -- 9.2 Bioconcentration, bioaccumulation, and biomagnification -- 9.3 Effects on aquatic animals -- 10. Regulations and standards -- 10.1 Occupational standards -- 10.2 Food tolerances -- 10.3 Transportation regulations -- 10.4 Water regulations -- 10.5 Solid waste regulations.