Record Display for the EPA National Library Catalog


Main Title International toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds /
Author Barnes, Donald G. ; Kutz, F. W. ; Bottimore, D. P. ; Greim, H. ; Grant, D. L.
CORP Author NATO Committee on the Challenges of Modern Society, Brussels (Belgium). ;Versar, Inc., Springfield, VA.;Environmental Protection Agency, Washington, DC. Office of Research and Development.
Publisher U.S. Environmental Protection Agency, Office of Research and Development : North Atlantic Treaty Organization, Committee on the Challenges of Modern Society,
Year Published 1988
Report Number EPA/600/6-90/009; NATO/CCMS-176; EPA-68-02-4254
Stock Number PB91-125625
Subjects Dioxins--Toxicology ; Dioxins--Environmental aspects
Additional Subjects Furans ; Chlorine aromatic compounds ; Toxicology ; Exposure ; Regulations ; Sediments ; Fly ash ; International Information Exchange ; Dioxin ; Risk assessment ; Isomers ; Solid wastes
Library Call Number Additional Info Location Last
NTIS  PB91-125625 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 35 pages : illustrations ; 28 cm
The International Toxicity Equivalency Factor (I-TEF) Method of Risk Assessment for Complex Mixtures of Dioxins and Related Compounds is a revised interim procedure for estimating the risks considered with exposures to mixtures of dioxins and furans such as incinerator fly ash, contaminated soil, and biological media. This updated method was developed by the Pilot Study on International Information Exchange on Dioxins and Related Compounds and has been adopted by the eight nation group as the preferred interim method. The I-TEF scheme should facilitate the exchange of information concerning the toxicological significance of contaminated samples between scientists and regulatory agencies worldwide. The method is based on the most recent toxicological data from a variety of biological responses including carcinogenicity, terctogenicity, immunotoxicity, lethality, and etymotic induction. The report describes the major differences in the new scheme compared to the numerous existing TEF schemes.
"Performing organization: University of Bayreuth." Includes bibliographical references. "Donald G. Barnes, chair and editor." Microfiche.