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Main Title Within-Session Changes in Peak N160 Amplitude of Flash Evoked Potentials in Rats(l,2).
Author Herr, D. W. ; King, D. ; Griffin, V. T. ; Watkinson, W. P. ; Boyes., W. K. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;ManTech Environmental Technology, Inc., Research Triangle
Publisher c1993
Year Published 1993
Report Number EPA/600/J-94/202;
Stock Number PB94-163813
Additional Subjects Animal physiology ; Amplitude modulation ; White noise ; Habituation(Learning) ; Conditioned stimulus ; Neurology ; Responses ; Arousal ; Pseudoconditioning ; Physiological effects ; Biomedical measurement ; Electroencephalography ; Statistical analysis ; Heart rate ; Rats ; Reprint ; FEPs(Flash evoked potentials) ; Peak N(160)
Library Call Number Additional Info Location Last
NTIS  PB94-163813 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 19p
The negative peak occurring approximately 160 ms after stimulation (peak N(160)) of flash evoked potentials (FEPs) of rats changes with repeated testing. Habituation, sensitization, and arousal have all been invoked to explain these changes, but few studies have directly tested these explanations. The authors examined within-session changes in peak N(160) amplitutde with repeated testing, and the modulatory effects of stimulus intensity and auditory white noise. Peak N(160) amplitude underwent within-session increases on early days and within-session decreases on later days. The within-session changes were not affected by stimulus intensity. The data suggest that the within-session changes in peak N(160) amplitude may reflect a habituation-like response to the test environment. (Copyright (c) 1993 Pergamon Press Ltd.)