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RECORD NUMBER: 4 OF 14

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Main Title

Effect of Polychlorinated Biphenyls on Rat Reproduction.

Author

Linder, R. E. ; Gaines, T. B. ; Kimbrough., R. D. ;

CORP Author

Environmental Protection Agency, Chamblee, Ga. Chamblee Toxicology Lab.

Year Published

1973

Stock Number

PB-279 186

Additional Subjects

Toxicology ; Pesticides ; Bioassay ; Exposure ; Laboratory animals ; Experimental data ; Rats ; Chlorine organic compounds ; Tables(Data) ; Reproduction(Biology) ; Pathology ; Dosage ; Diets ; Mortality ; Liver ; Histology ; Lethal dosage ; Physiological effects ; Aroclor 1254 ; Reprints ; Polychlorinated biphenyls ; Aroclor 1260 ; Biphenyl/hexachloro ; Biphenyl/chloro ; Toxic substances

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB-279 186	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

16p

Abstract

The present investigation was initiated in 1970 to study the effects on reproduction and pathology produced by two American-made PCB mixtures sold under the trade-names Aroclor 1254 and Aroclor 1260. Aroclor 1254 contains 54% (w/w) chlorine and is composed of 11% tetra-, 49% penta-, 34% hexa- and 6% heptachlorobiphenyls; Aroclor 1260 has 60% (w/w) chlorine, with a composition of 12% penta-, 38% hexa-, 41% septa-, 8% octa- and 1% nonochlorobiphenyls. The present communication is an account of reproduction studies in rats. Also included are acute toxicity values from preliminary studies and comments on pathology and haematology in animals from the reproduction experiments.

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