Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Responses of Subjects with Chronic Obstructive Pulmonary Disease after Exposures to 0.3 PPM Ozone.
Author Kehrl, H. R. ; Hazucha, M. J. ; Solic, J. J. ; Bromberg, P. A. ;
CORP Author North Carolina Univ. at Chapel Hill. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA-R-807392; EPA/600/J-85/084;
Stock Number PB85-237675
Additional Subjects Ozone ; Toxicology ; Respiratory diseases ; Responses ; Exposure ; Smoking ; Exercise(Physiology) ; Reprints ; Air pollution effects(Humans) ; Chronic obstructive lung disease
Library Call Number Additional Info Location Last
NTIS  PB85-237675 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 7p
The authors previously reported (1982) that the respiratory mechanics of intermittently exercising persons with chronic obstructive pulmonary disease (COPD) were unaffected by a 2-h exposure to 0.2 ppm ozone. Employing a single-blind cross-over design protocol, 13 white men with nonreversible COPD were randomly exposed on two consecutive days for 2 h to air and 0.3 ppm ozone. During exposures, subjects exercised for 7.5 min every 30 min; ventilation and gas exchange measured during exercise showed no difference between exposure days. Pulmonary function tests (spirometry, body plethysmography) obtained before and after exposures were unchanged on the air day.