Presentations given at the Conference on Abnormal Functional Development of the Heart, Lungs, and Kidneys are documented in this publication. The meeting was sponsored by the U.S. Environmental Protection Agency and was held in Asheville, NC, May 11-13, 1983. In an attempt to carry over the flavor of informality and exchange of ideas of the conference, in this document the authors have grouped the articles by main subject area (General, Lungs, Heart, and Kidneys) and have concluded each grouping with an edited summary of the often lively discussion of those presentations that transpired at the conference.