Record Display for the EPA National Library Catalog


Main Title Cell Number and Size in Selected Organs of Fetuses of Rats Malnourished and Exposed to Nitrofen.
Author Zeman, F. J. ; Heng, H. ; Hoogenboom, E. R. ; Mahboob, S. ; Kavlock, R. J. ;
CORP Author California Univ., Davis. Dept. of Nutrition.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1986
Report Number EPA-R-810526; EPA/600/J-86/463;
Stock Number PB88-214671
Additional Subjects Exposure ; Toxicology ; Embryos ; Rats ; Laboratory animals ; Reproduction(Biology) ; Concentration(Composition) ; Toxicity ; Congenital abnormalities ; Nitrofen ; Carcinogenesis ; Biological effects
Library Call Number Additional Info Location Last
NTIS  PB88-214671 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
The effects of maternal exposure to nitrofen or protein-energy malnutrition on the number and sizes of cells in selected organs of the fetal rat have been studied. Pregnant rats were fed either an adequate (CON) or protein-energy deficient diet (PEM) throughout gestation. Maternal nitrofen exposure resulted in reduced weight and reduced protein in all organs except the brain. The data indicate that maternal protein-energy malnutrition results in smaller organs in the fetuses with fewer cells and containing less protein and RNA. The greater reduction in protein than that expected from the decrease in numbers of cells in the liver, intestine, and brain in fetuses of malnourished dams suggest that cells were also smaller. (Copyright (c) 1986 Alan R. Liss, Inc.)