Record Display for the EPA National Library CatalogRECORD NUMBER: 17 OF 27
|Main Title||Maternal Hepatic and Embryonic Effects of 1,2,3,4-Tetrachlorobenzene in the Rat.|
|Author||Kitchin, K. T. ; Ebron, M. R. ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Toxicology ; Embryos ; Liver ; Rats ; Laboratory animals ; Ingestion(Biology) ; Pregnancy ; Reprints ; Benzene/tetrachloro ; Toxic substances|
To assess possible maternal hepatic and reproductive effects of this uncharged, low molecular weight, lipophilic chlorinated bezene 0,100, 300 and 1000 mg/kg/day of 1,2,3,4,-tetrachlorobenzene (TCB) was orally administered to pregnant rats on days 9 -13 of gestation and the animals were killed on day 14 of pregnancy. Phenobarbital and beta-naphthoflavone were administered to other pregnant rats as positive hepatic controls.