Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Principles of Developmental Toxicity Risk Assessment.
Author Kimmel, C. A. ; Kimmel, G. L. ;
CORP Author Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment.
Publisher Aug 95
Year Published 1995
Report Number EPA/600/A-95/110 ;NCEA-W-026;
Stock Number PB95-274221
Additional Subjects Toxicity ; Risk assessment ; Health risks ; Environmental effects ; Exposure ; Toxic substances ; Standards ; Dose-response relationships ; Data bases ; Models ; Dosage ; Research ; Requirements ; Biological effects ; Developmental toxicology ; Noncancer ; Nonmutagenic
Library Call Number Additional Info Location Last
NTIS  PB95-274221 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 11/25/1995
Collation 69p
Developmental toxicity testing over the last three decades has provided considerable data that have been used by regulatory agencies to set standards and to regulate exposures. As part of a larger guidelines effort, the Environmental Protection Agency (EPA) published guidelines for developmental toxicity risk assessment, first in 1986 and again in 1991. This was the first guidelines developed to describe a consistent approach for noncancer and nonmutagenic risk assessment. This chapter focuses on the risk assessment process used for developmental toxicity by EPA, although the guidelines represent a consensus document within the field of developmental toxicology. Three major components are discussed: hazard identification/dose-response evaluation, exposure assessment, and risk characterization.