Record Display for the EPA National Library Catalog


Main Title Differing Response of Asthmatics to Sulfur Dioxide Exposure with Continuous and Intermittent Exercise.
Author Kehrl, H. R. ; Roger, L. J. ; Hazucha, M. J. ; Horstman, D. H. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Clinical Research Branch.
Year Published 1986
Report Number EPA/600/J-87/026;
Stock Number PB87-198487
Additional Subjects Respiratory diseases ; Asthma ; Exercise(Physiology) ; Sulfur dioxide ; Exposure ; Air pollution ; Ventilation ; Respiration ; Performance tests ; Reprints ; Dose rate ;
Library Call Number Additional Info Location Last
NTIS  PB87-198487 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Ten mild asthmatics were initially exposed in an environmental chamber (26 c, 70% RH) to clean air and 1.0 ppm sulfur dioxide while performing three sets of 10 minutes treadmill exercise (ventilation = 41 1/min) and 15 minutes rest. To evaluate the effects of the pattern and duration of exercise on the response to sulfur dioxide exposure, the subjects were then exposed to the same environmental conditions, while exercising continuously for 30 minutes. Specific airways resistance (SRaw) was measured by body plethysmography prior to exposures and after each exercise. All SRaw responses with sulfur dioxide exposure were significantly different than the clean air responses. It appears that asthmatics show an attenuated response to repetitive exercise in a 1.00 ppm sulfur dioxide atmosphere and that the response to sulfur dioxide exposure develops rapidly and is maintained during 30 minutes continuous exercise.