Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Sensitivity of Vertebrate Embryos to Heavy Metals as a Criterion of Water Quality-Phase I.
Author Birge, Wesley J. ; Just, John J. ; Westerman, Albert ; Rose., A. Duane ;
CORP Author Kentucky Water Resources Inst., Lexington.
Year Published 1973
Report Number RR-71; DI-14-31-0001-3890; OWRR-B-028-KY; W74-07715 ; OWRR-B-028-KY(1)
Stock Number PB-232 075
Additional Subjects Embryos ; Indicator species ; Toxic diseases ; Lethal dosage ; Birds ; Amphibians ; Fishes ; Mercury(Metal) ; Cadmium ; Lead ; Trout ; Catfishes ; Abnormalities ; Water quality ; Heavy metals ; Water pollution effects(Animals) ; Bioindicators ; Goldfish
Library Call Number Additional Info Location Last
NTIS  PB-232 075 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 38p
Avian, amphibian and fish embryos were given continuous treatment with inorganic mercury, methyl mercury, cadmium and lead, to determine the sensitivity of embryogenesis to metallic poisoning. All metals produced substantial degrees of lethality and/or gross anatomical anomalies at 10 ppb or less. Treatment with inorganic mercury at 10 ppb produced 100% kill of frog embryos. Chick and rainbow trout embryos suffered 10-20% lethality when exposed to 1 ppb of either inorganic or methyl mercury. Lead and cadmium at 1 ppb produced 24-32% lethality in chick embryos. No significant differences were observed in the embryopathic effects of inorganic or methyl mercury. Concerning the toxic effects of mercury, cadmium and lead, the 'embryonic stage' appears to constitute the critical 'sensitive link' in the vertebrate life cycle. The reporductive potential of vertebrate populations may be severely restricted (e.g., embryonic mortality) by such pollutants at trace levels which may not prove hazardous to adult animals.