Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Chronic Ingestion of Mn3O4 by Rats: Tissue Accumulation and Distribution of Manganese in Two Generations.
Author Rehnberg, Georgia L. ; Hein, Joy F. ; Carter,, Susan D. ; Linko, Richard S. ; Laskey, John W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div.
Year Published 1982
Report Number EPA-600/J-82-258;
Stock Number PB83-140889
Additional Subjects Manganese oxides ; Toxicology ; Rats ; Laboratory animals ; Diets ; Ingestion(Biology) ; Tissues(Biology) ; Reprints ; Bioaccumulation ; Particulates
Library Call Number Additional Info Location Last
NTIS  PB83-140889 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 16p
Sprague-Dawley rats were chronically exposed to particulate Mn3O4 through two generations. At specific ages, observations were made of growth, tissue content, and distribution of Mn and Fe as affected by chronic exposure to Mn through an Fe-sufficient diet and an Fe-deficient diet. Chronic dietary Mn3O4 resulted in dose-related increases in Mn accumulation, and a concomitant Fe deficiency promoted Mn accumulation. In general, the addition of substantial amounts of Mn to either diet depressed tissue Fe levels.