Record Display for the EPA National Library Catalog

RECORD NUMBER: 6 OF 12

OLS Field Name OLS Field Data
Main Title Identification of Deoxynucleoside; Polyaromatic Hydrocarbon Adducts by Capillary Zone Electrophoresis; Continuous Flow-Fast Atom Bombardment Mass Spectrometry.
Author Wolf, S. M. ; Vouros, R. ; Norwood, C. ; Jackim, E. ;
CORP Author Northeastern Univ., Boston, MA. Barnett Inst. of Chemical Analysis and Materials Science.;Environmental Research Lab., Narragansett, RI.;National Institutes of Health, Bethesda, MD.;Arthur D. Little Foundation, Cambridge, MA.;Society of Analytical Chemists of Pittsburgh, PA.
Publisher c1992
Year Published 1992
Report Number PUB-509; EPA/600/J-93/314 ; ERLN-1416
Stock Number PB93-229367
Additional Subjects Deoxyguanosine ; Aromatic polycyclic hydrocarbons ; Electrophoresis ; Fast atom bombardment mass spectrometry ; Mutagens ; Molecular weight ; DNA damage ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB93-229367 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 11/22/1993
Collation 7p
Abstract
Capillary zone electrophoresis coupled to continuous flow-fast atom bombardment mass spectrometry is shown to have utility for the detection and characterization of adducts formed by the covalent attachment of four polyaromatic hydrocarbon (PAH) and amino-PAH compounds to deoxyguanosine. Normal scanning provided structural information for a 1.3 ng injection of a model adduct, while 1.3 ng of each of a mixture of adducts was sufficient to determine their molecular weights by monitoring the constant neutral loss of deoxyribose. Exploitation of this loss in the multiple reaction monitoring mode resulted in the detection of low picogram amounts of target adducts in mixtures. (Copyright (c) 1992 American Society for Mass Spectrometry.)