Record Display for the EPA National Library Catalog

RECORD NUMBER: 14 OF 21

OLS Field Name OLS Field Data
Main Title Pulmonary Effects of Ozone Exposure during Exercise: Dose-Response Characteristics.
Author McDonnell, W. F. ; Horstman, D. H. ; Hazucha, M. J. ; Seal, Jr., E. ; Haak, E. D. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill.
Year Published 1982
Report Number EPA-600/J-83-062;
Stock Number PB84-101757
Additional Subjects Ozone ; Toxicology ; Exercise(Physiology) ; Males ; Humans ; Exposure ; Concentration(Composition) ; Responses ; Dosage ; Reprints ; Air pollution effects(Humans)
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB84-101757 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Abstract
Because minimal data are available regarding the pulmonary effects of ozone (O3) at levels < 0.27 ppm, six groups of healthy young males were exposed for 2.5 h to one of the following O3 concentrations:0.0, 0.12, 0.18, 0.24, 0.30, or 0.40 ppm. Fifteen-minute periods of rest and exercise (65 1/min minute ventilation) were alternated during the first 2 h of exposure. Coughing was observed at all levels of O3 exposure. Small changes in forced-expiratory spirometric variables spirometic variables (forced vital capacity (FVC), forced expiratory volume in 1s, and mean expiratory flow rate between 25 and 75% FVC) were observed at 0.12 and 0.18 ppm O3, and larger changes were found at O3 levels greater than or equal to 0.24 ppm. Changes in tidal volume and respiratory frequency during exercise, specific airway resistance, the presence of pain on deep inspiration, and shortness of breath occurred at O3 levels greater than or equal to 0.24 ppm.