| Main Title |
Synthesis and Reactions of a Proposed DDT Metabolite, 2,2-bis(p-Chlorophenyl)acetaldehyde. |
| Author |
McKinney, J. D. ;
Boozer, E. L. ;
Hopkins, H. P. ;
Suggs., J. E. ;
|
| CORP Author |
Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch. |
| Year Published |
1969 |
| Stock Number |
PB-274 740 |
| Additional Subjects |
Pesticides ;
Synthesis(Chemistry) ;
Chlorine organic compounds ;
Metabolism ;
Chemical reactions ;
Reprints ;
Acetaldehyde/dichloro-diphenyl
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-274 740 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
2p |
| Abstract |
Studies of the metabolism of DDT led to the preparation of 2,2-bis(p-chlorophenyl)acetaldehyde (I) in order to investigate the possibility of its intermediacy in DDT metabolism. Results of attempts to reproduce a reported synthesis of I have shown that both this report and an even earlier report of a different synthetic approach are incorrect. It was observed in this laboratory that I undergoes oxidative deformylation under mild oxidizing conditions to form the benzophenone (II). In comparison, the o,o'-isomer was quite stable under the same conditions. These results are of theoretical interest and may have biological significance. |
