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Main Title Natural Abundance 13C NMR Spectroscopy of Double-Stranded DNA.
Author Rill, Randolph L. ; Hillard, Jr., Peter R. ; Bailey, J. Terry ; Levy, George C. ;
CORP Author Florida State Univ., Tallahassee. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1979
Report Number EPA-R-804916; EPA-600/J-80-381;
Stock Number PB82-155268
Additional Subjects Nuclear magnetic resonance ; Deoxyribonucleic acids ; Failure ; Performance evaluation ; Reprints ; Isotopic labeling ; Carbon 13
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB82-155268 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
Abstract
Although 13C NMR spectroscopy has already proved extremely useful in studies of biopolymers, including t-RNA's, and single-stranded polynucleotides, no successful study of native double-stranded DNA has been reported. This failure is mainly due to extremely unfavorable 13C spin relaxation parameters (very short T2's and long T1's) expected for the long and relatively rigid chains of typical DNA preparations.