Record Display for the EPA National Library Catalog


Main Title Pathologic Changes in the Liver of Rats after Feeding Low Levels of Various Insecticides.
Author Ortega, Paul ; Hayes, Wayland J. ; Durham., William F. ;
CORP Author Communicable Disease Center, Savannah, Ga.
Year Published 1957
Stock Number PB-279 717
Additional Subjects Pesticides ; Toxicology ; Morbidity ; Mortality ; Liver ; Rats ; Pathology ; Ingestion(Biology) ; Insecticides ; Body weight ; Diet ; Laboratory animals ; Experimental data ; Tissues(Biology) ; Kidney ; Spleen ; Dieldrin ; Chlordan ; Dosage ; Toxicity ; Reprints ; Lindane ; Toxaphene ; Toxic substances
Library Call Number Additional Info Location Last
NTIS  PB-279 717 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
In order to reinvestigate the minimal dietary levels of certain chlorinated hydrocarbon insecticides required to produce pathologic change, materials were fed to rats at the following concentrations: Chlordane, 2.5 and 25 ppm; Dieldrin, 2.5 and 25 ppm; lindane, 50 and 100 ppm; and Toxaphene, 50 and 200 ppm. The control diet contained less than 0.6 ppm of D.D.T. as the only known contaminating insecticide. The experimental animals were observed clinically and then serially killed after from two to nine months' exposure to the poison. Tissues from liver, kidney, and spleen were examined histologically. (Portions of this document are not fully legible)