Record Display for the EPA National Library CatalogRECORD NUMBER: 6 OF 8
|Main Title||Tumors of the Central Nervous System, Volume 1 Gliomas: Glioblastoma (Part 1) / [electronic resource] :|
|Author||Hayat, M. A.|
|Subjects||Medicine ; Oncology ; Radiology, Medical ; Neurosurgery ; Pathology|
|Collation||XXII, 434 p. online resource.|
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed.