Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 10

Main Title Proliferative hepatocellular lesions of the rat : review and future use in risk assessment /
Author Rinde, Ester. ; Hill, R. ; Chiu, A. ; Haberman, B.
Other Authors
Author Title of a Work
Rinde, Esther.
CORP Author United States. Enviornmental Protection Agency. Risk Assessment Forum.
Publisher Environmental Protection Agency,
Year Published 1986
Report Number EPA/625/3-86/011
Stock Number PB87-178711
OCLC Number 15719293
Subjects Risk assessment. ; Carcinogenicity testing.
Additional Subjects Risk assessment ; Liver neoplasms ; Carcinogens ; Malignant neoplasms ; Liver diseases ; Liver ; Neoplasms ; Rats
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=300047AB.PDF
http://www.epa.gov/raf/publications/proliferative-hepatocellular-lesions-rats.htm
Local Library Info
Library Local Subject Local Note
EKB Photocopy.
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EHAM  QL737.R6 p2 Region 1 Library/Boston,MA 04/29/2016
EIAD  EPA/625/3-86/011 Region 2 Library/New York,NY 10/02/2003 DISPERSAL
EJBD ARCHIVE EPA 625-3-86-011 Headquarters Library/Washington,DC 01/25/2011
EJBD  EPA 625-3-86-011 Headquarters Library/Washington,DC 09/25/2018
EKBD  EPA-625/3-86-011 Research Triangle Park Library/RTP, NC 06/04/2012
EKCD  EPA/625/3-86/011 CEMM/GEMMD Library/Gulf Breeze,FL 11/20/2018
ERAD  EPA 825/3-86-011 Region 9 Library/San Francisco,CA 11/20/1998
ESAD  EPA 625-3-86-011 Region 10 Library/Seattle,WA 05/31/2017
NTIS  PB87-178711 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 22 pages ; 28 cm
Abstract
The paper addresses three questions that are crucial in the evaluation of rat tumor data and in the assessment of carcinogenic risk for humans. One question is whether to consider these lesions 'hyperplastic' or 'neoplastic' in nature, the latter classification being indicative of tumor formation. A second question is to interpret the finding that in some experimental systems, certain nonmalignant proliferative lesions may regress following removal of an inciting, carcinogenic stimulus, with only a small proportion of the lesions persisting. Finally, it is important to know whether any of these lesions may progress to carcinoma.
Notes
"EPA/625/3-86/011." "February 1986." Includes bibliographical references (pages 18-22).