Record Display for the EPA National Library Catalog


Main Title Radon Progeny Dosimetry in the Rat Lung.
Author Hofmann, W. ; Menache, M. G. ; Graham, R. C. ;
CORP Author Duke Univ. Medical Center, Durham, NC. Center for Extrapolation Modelling. ;ManTech Environmental Technology, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div.
Publisher c1993
Year Published 1993
Report Number EPA-R-813113; EPA/600/J-94/049;
Stock Number PB94-137056
Additional Subjects Radon ; Dosimetry ; Lung ; Dose-response relationships ; Rats ; Radiation-induced neoplasms ; Aerosols ; Bronchi ; Trachea ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB94-137056 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Deposition, mucociliary clearance, and dosimetry for the inhalation of radon progeny in the rat lung have been simulated for a variety of inhalation conditions. Computations indicate that the exposure-dose conversion factor for the rat lung is approximately twice as high as the corresponding value for the human lung for the same exposure conditions. However, if typical aerosol characteristics are used for animal inhalation experiments and human indoor exposures, the resulting exposure-dose conversion factors are comparable, thereby suggesting similar lung cancer risks per unit exposure. The predicted relative effects of radon progeny disequilibrium and unattached fractions on bronchial doses agree with results from inhalation experiments with laboratory rats. (Copyright (c) 1993 Health Physics Society.)