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RECORD NUMBER: 3 OF 3

Main Title Possible Animal Models of Follicular Development Relevant to Reproductive Toxicology.
Author Greenwald, G. S. ;
CORP Author Kansas Univ. Medical Center, Kansas City.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher c1987
Year Published 1987
Report Number EPA/600/J-87/474 ; OHEA-R-250
Stock Number PB89-201891
Additional Subjects Reproduction(Biology) ; Toxicology ; Laboratory animals ; Rats ; Reproductive system ; Ovary ; Reprints ; Follicles ; Estrous cycle ; Toxic substances
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NTIS  PB89-201891 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Abstract
Models of follicular development in rodents that may be applicable to reproductive toxicology are considered. The value of evaluating changes in follicular numbers during the estrous cycle is stressed. Most of the methods involve in vivo manipulations. However, the use of enzymes to dissociate intact follicles from the ovary and their subsequent in vitro development in the presence or absence of xenobiotics offers an alternative, attractive approach. (Copyright (c) 1987 Pergamon Journals Ltd.)