| Main Title |
Risk assessment of complex mixtures / |
| Author |
Gibb, Herman J. ;
Gibb, H. J. ;
Chen, C. W.
|
| Other Authors |
|
| CORP Author |
Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Publisher |
Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, |
| Year Published |
1984 |
| Report Number |
EPA-600/D-84-186 |
| Stock Number |
PB84-223478 |
| OCLC Number |
70515222 |
| Subjects |
Water--Analysis--Mathematical models ;
Hazardous substances--Risk assessment ;
Water--Pollution--Mathematical models ;
Carcinogens--Environmental aspects--Measurement
|
| Additional Subjects |
Effluents ;
Epidemiology ;
Assessments ;
Carcinogenesis ;
Risk assessment
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD ARCHIVE |
EPA 600-D-84-186 |
|
Headquarters Library/Washington,DC |
07/06/2010 |
| NTIS |
PB84-223478 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
[20] leaves : ill. ; 28 cm. |
| Abstract |
Quantitative carcinogenic assessment of complex mixtures is complicated by the variability of the mixtures. Different samples of effluents from the same source may vary in their carcinogenic potency. A multiplicative effect could be produced by the action of different fractions of a mixture on different stages of the carcinogenic process. A mathematical formula explaining this multiplicative effect is presented here. Antagonism may result from the action of different fractions on the same stage. Actual data from both epidemiologic studies and animal investigations are used for illustration. |
| Notes |
Caption title. "EPA-600/D-84-186". "PB84-223478". Includes bibliographical references (leaves [11]-[14]). Photocopy. |
