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Main Title Superfund Innovative Technology Evaluation (SITE) report for the Westinghouse bio-analytic systems pentachlorophenol immunoassays /
Author Silverstein, M. E. ; White, R. J. ; Gerlach, R. W. ; Van Emon, J. M.
Other Authors
Author Title of a Work
Silverstein, M. E.
CORP Author Lockheed Engineering and Sciences Co., Inc., Las Vegas, NV. Environmental Programs Office.;Environmental Monitoring Systems Lab., Las Vegas, NV.
Publisher Environmental Monitoring Systems Laboratory, Office of Research and Development, U.S. Environmental Protection Agency,
Year Published 1992
Report Number EPA/600/R-92/032; EPA-68-03-3249; EPA-68-CO-0049
Stock Number PB92-188713
OCLC Number 29212183
Subjects Pentachlorophenol
Additional Subjects Superfund Innovative Technology Evaluation Program (US) ; Pentachlorophenol ; Immunoassay ; Quality control ; Mass fragmentography ; Chemical water pollutants ; Cross reactions ; Antibodies ; SITE(Superfund Innovative Technology Evaluation)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EMBD  EPA/600/R-92/032 NRMRL/GWERD Library/Ada,OK 02/03/1995
NTIS  PB92-188713 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation xv, 93 pages : illustrations ; 28 cm
The results of the demonstration of two Westinghouse Bio-Analytic Systems (WBAS) immunoassay technologies are described in the report. The immunoassays measure parts per billion concentrations of pentachlorophenol in environmental water samples. The study was conducted under the Superfund innovative Technology Evaluation (SITE) Program and designed to evaluate the ruggedness and utility of a semiquantitative immunoassay field kit. Results obtained from the field kit were compared to those obtained from a quantitative, high-sample-capacity plate immunoassay. The results of the WBAS immunoassay demonstration support the conclusion that the field immunoassay is a useful screening tool. The demonstration verified that the method can provide qualitative or semiquantitative screening information. Although the results were more variable than had been anticipated, the incorporation of additional procedural precautions and carefully chosen quality control acceptance criteria for on-site analysis could improve performance substantially. Both immunoassays produced results biased high compared to the GC/MS results, but the tendency was not large and may have been partly due to loss during sample extraction (EPA Method 3510) prior to analysis by gas chromatography/mass spectrometry. The detection of structurally related compounds by the immunoassays may have also contributed to the high bias. The results indicate that the plate immunoassay is an accurate and precise method for quantitating pentachlorophenol in water.
Includes bibliographical references (p. 65-66).