Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Detection of mutagenic properties of pesticides used in commercial corn production. {MICROFICHE}
Author Plewa, Michael J. ; Gentile, James M.
CORP Author Illinois Univ. at Urbana-Champaign. Inst. for Environmental Studies.;Health Effects Research Lab., Research Triangle Park, NC. ;Hope Coll., Holland, MI. Dept. of Biology.
Publisher Institute for Environmental Studies, University of Illinois for US Environmental Protection Agency
Year Published 1983
Report Number EPA-68-02-2704; EPA-600/1-83-006
Stock Number PB83-226118
Subjects Pesticides
Additional Subjects Pesticides ; Corn ; Herbicides ; Toxicology ; Detection ; Bioassay ; Mutations ; Bacteria ; Mutagenesis ; Genotoxicity ; Bioindicators
Library Call Number Additional Info Location Last
NTIS  PB83-226118 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 212 p. : graphs ; 28 cm.
This project encompassed the analysis of 21 pesticides and 12 combinations of herbicides for their genotoxic properties. Three genetic assays were employed: reverse mutation in Salmonella typhimurium, gene conversion in S. cerveisiae and reverse mutation in Z. mays. The use of these genetic indicator organisms established a comprehensive data base that resolved a spectrum of genetic damage induced by single agents or by combination of agents. The pesticides were evaluated with the microbial assays directly, after in vitro mammalian microsomal activation and after in vivo plant activation protocols. Finally all the pesticides were tested for their ability to induce mutations in Z. mays under in situ (in field) conditions.
Supported in part by the U.S. Dept. of the Interior, Office of Water Research and Technology. "EPA600/1-83/006". Microfiche.