Record Display for the EPA National Library Catalog

RECORD NUMBER: 11 OF 14

OLS Field Name OLS Field Data
Main Title Potential industrial carcinogens and mutagens /
Author Fishbein, L.
CORP Author United States. Environmental Protection Agency. Office of Toxic Substances.; National Center for Toxicological Research.; Environmental Protection Agency, Washington, D.C. Office of Toxic Substances.
Publisher Environmental Protection Agency, Office of Toxic Substances ; For sale by the National Technical Information Service,
Year Published 1977
Report Number EPA 560/5-77-005
Stock Number 22161
OCLC Number 03201450
ISBN pbk.
Subjects Carcinogens. ; Mutagenesis.
Additional Subjects Carcinogens ; Mutagenesis ; Assessments ; Carcinogens ; Mutagens ; Industrial hygiene ; Organic compounds ; Industrial wastes ; Hazardous materials ; Environmental surveys ; Microorganisms ; Bioassay ; Public health ; Alkylation ; Amines ; Azo dyes ; Hydroxylamine ; Hydrazines ; Carbamates ; Epoxides ; Lactones ; Sulfates ; Sultones ; Aldehydes ; Ethers ; Nitros compounds ; Aromatic compounds ; Polymers ; Hydrocarbons ; Halogen organic compounds ; Alkanols ; Halides ; Esters ; Phosphoric acids ; Acylation ; Furans ; Aromatic hydrocarbons ; Azides ; Anthraquinones ; Toxicology ; Molecular structures ; Utilization ; Aziridines ; Triazenes ; Carcinogenesis ; Cancer
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=91022F88.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD ARCHIVE EPA 560/5-77-005 Headquarters Library/Washington,DC 06/10/2016
EJBD  EPA 560/5-77-005 Headquarters Library/Washington,DC 05/28/2004
EJED  EPA 560/5-77-005 OCSPP Chemical Library/Washington,DC 01/01/1988
EKAM  RC268.5.F5 Region 4 Library/Atlanta,GA 01/17/1997
ESAD  EPA 560-5-77-005 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB-273 197 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 316 pages : illustrations ; 28 cm.
Abstract
Ninety industrial chemicals, illustrative of 16 major classes and 19 structural sub-categories have been reviewed primarily in terms of their reported carcinogenicity and/or mutagenicity. The compounds were selected based on factors including: their reported carcinogenicity and/or mutagenicity, their chemical structures and relationships to known carcinogens or mutagens, their volume or use characteristics, and suggested or estimated potential populations at risk. Additionally, germane aspects (where known) of their synthesis (primarily in terms of the nature of the possible hazardous trace impurities), use patterns, chemical and biological reactivity and stability, environmental occurrence and metabolic fate have been included for cohesiveness of treatment. It is important to note that in 52 of the above cases, both carcinogenicity and mutagenicity of individual compounds were reported. Thirty-one compounds have been reported to be mutagenic and noncarcinogenic and seven compounds are carcinogenic and nonmutagenic. In a number of cases, there are no reports of a compound having been tested for carcinogenicity or mutagenicity or they are currently on test. In some cases, conflicting carcinogenicity and/or mutagenicity results for the same compound were reported. The largest number of industrial agents that have been reported to be carcinogenic and/or mutagenic are alkylating and acylating agents classified under 12 structural headings.
Notes
Prepared by National Center for Toxicological Research, Jefferson, Ark., under contract no. EPA-IAG-D4-0472. Issued May 5, 1977. Includes bibliographical references.