Record Display for the EPA National Library Catalog


Main Title Eye irritation testing : an assessment of methods and guidelines for testing materials for eye irritancy /
Author Falahee, K. J. ; Rose, C. S. ; Olin, S. S. ; Seifried, H. E.
CORP Author United States. Environmental Protection Agency. Office of Pesticides and Toxic Substances.
Publisher Distributed by National Technical Information Service,
Year Published 1981
Report Number EPA-560/11/82-001; EPA-68-01-6176
Stock Number PB82-225764
OCLC Number 09750254
Subjects Toxicology--Methods ; Toxicology, Experimental
Additional Subjects Toxicology--Methods ; Toxicology, experimental ; Eye injuries ; Assessments ; Rabbits ; Bioassay ; Laboratory animals ; In vivo analysis ; In vitro analysis ; Tests ; Guidelines ; Methodology ; Irritants ; Toxic substances ; Draize method ; Tier testing
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJED  EPA 560-11-82-001 OCSPP Chemical Library/Washington,DC 10/08/2004
ELBD ARCHIVE EPA 560-11-82-001 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ELBD RPS EPA 560-11-82-001 repository copy AWBERC Library/Cincinnati,OH 03/21/2016
ELBD  EPA 560-11-82-001 AWBERC Library/Cincinnati,OH 03/23/2016
NTIS  PB82-225764 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation xii, 83 pages : illustrations ; 28 cm
The ocular safety of materials is determined primarily by observing the irritation produced by test agents instilled directly into the rabbit eye. The object of this study was to review the scientific basis for published guidelines, particularly those recently developed by the Organization for Economic Cooperation and Development (OECD) and the Interagency Regulatory Liaison Group (IRLG). These guidelines are essentially the same and recommend instillation of 0.1 ml material into the rabbit eye with observation for at least 72 hr.
Contract no.: 68-01-6176. Report no.: EPA 560/11-82-001. Project officer: Charles Auer. Technical advisors: Norbert P. Page, Daljit Sawhney. Prepared by Tracor Jitco, Inc. Includes bibliographical references (pages 63-72).