During 1982, the authors examined the health and environmental programs of eighteen states to assess state capabilities and common needs with respect to identifying and solving cross-media toxic substances problems. Discussions with a variety of state officials covered such areas as statutory and executive authorities, organizational structures, data management and toxics control efforts. In addition, problems and issues such as proprietary information, risk assessment, and resource cutbacks sometimes surfaced. Using this information, the State Profiles were prepared. Drafts of the Profiles were reviewed by officials in the respective states, and their comments have been incorporated into this document. In addition, drafts were reviewed by selected EPA Regional and program office staff; EPA comments are incorporated also.