Record Display for the EPA National Library Catalog

RECORD NUMBER: 29 OF 34

Main Title Toxicokinetic Modeling of (14)C-Pentachlorophenol in the Rainbow Trout ('Salmo gairdneri).
Author McKim, J. M. ; Schmieder, P. K. ; Erickson, R. J. ;
CORP Author Environmental Research Lab.-Duluth, MN.
Year Published 1986
Report Number EPA/600/J-86/295;
Stock Number PB87-176434
Additional Subjects Fishes ; Toxicology ; Absorption ; Metabolism ; Elimination ; Dosimetry ; Reaction kinetics ; Reprints ; Pentachlorophenol ; Water pollution effects(Animals) ; Bioconcentration ; Xenobiotics ; Risk assessment
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NTIS  PB87-176434 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 24p
Abstract
An in vivo trout model was used to monito the major routes and rates of pentachlorophenol uptake and elimination. A first-order kinetic model and observed data were used to generate fitted and predicted rate constants required for evaluation of first-order kinetic. The fitted first-order uptake-depuration curves for all experimental animals agreed with those observed suggesting first-order kinetics approximated the behavior of whole-body (14)C-pentachlorophenol (PCP) burden.