Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Effects of Exposure to Ozone on Susceptibility to Experimental Tuberculosis.
Author Thomas, Gail ; Fenter, James ; Ehrlich, R. ; Gardner, D. E. ;
CORP Author IIT Research Inst., Chicago, IL. Life Sciences Research Div.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-68-02-1273; EPA-600/J-81-645;
Stock Number PB83-243311
Additional Subjects Ozone ; Toxicology ; Mice ; Laboratory animals ; Bacteria ; Lung ; Guinea pigs ; Response ; Reprints ; Mycobacterium tuberculosis ; Hypersensitivity ; Air pollution effects(Animals)
Library Call Number Additional Info Location Last
NTIS  PB83-243311 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Exposure of mice to 1.96 mg/cu. m. ozone (03) 3 h/day, 5 days/week, for up to 8 weeks beginning at 1 or 2 weeks after challenge with Mycobacterium tuberculosis R1Rv resulted in significant enhancement of bacterial titers in the lungs at 5 through 8 weeks after challenge when compared to mice compared to controls. Exposure of guinea pigs to 2.9 mg/cu. m 03 for 3 h immediately after challenge with M. tuberculosis resulted in a suppression of the cutaneous delayed hypersensitivity response, without affecting the serum hemagglutination antibody titers. However, exposure of guinea pigs to 0.98 mg/cu. m 03 3h/day for 5 days, initiated within 3 h after the infectious challenge, enhanced hemagglutination antibody titers initially, but the delayed hypersensitivity reaction did not differ from controls.