Includes bibliographical references and index.

Unit I: General principles of toxicology -- History and scope of toxicology / Michael A. Gallo -- Principles of toxicology / David L. Eaton and Steven G. Gilbert -- Mechanisms of toxicity / Zoltan Gregus -- Risk assessment / Elaine M. Faustman and Gilbert S. Omenn -- Unit II: Disposition of toxicants -- Absorption, Distribution, and excretion of toxicants / Lois D. Lehman-McKeeman -- Biotransformation of xenobiotics / Andrew Parkinson and Brian W. Ogilvie -- Toxicokinetics / Danny D. Shen- Unit III: Non-organ-directed toxicity -- Chemical carcinogens / James E. Klaunig and Lisa M. Kamendulis -- Genetic toxicology / R. Julian Preston and George R. Hoffmann -- Developmental toxicology / John M. Rogers and Robert J. Kavlock -- Unit IV: Target organ toxicity -- Toxic responses of the blood / John C. Bloom and John T. Brandt -- Toxic responses of the immune system / Norbert E. Kaminski [and others] -- Toxic responses of the liver / Hartmut Jaeschke -- Toxic responses of the kidney / Rick G. Schnellmann -- Toxic responses of the respiratory system / Hanspeter R. Witschi [and others] -- Toxic responses of the nervous system / Virginia C. Moser [and others] -- Toxic responses of the ocular and visual system / Donald A. Fox and William K. Boyes -- Toxic responses of the heart and vascular system / Y. James Kang -- Toxic responses of the skin / Robert H. Rice and Theodora M. Mauro -- Toxic responses of the reproductive system / Paul M.D. Foster and L. Earl Gray Jr. -- Toxic responses of the endocrine system / Charles C. Capen -- Unit V: Toxic agents -- Toxic effects of pesticides / Lucio G. Costa -- Toxic effects of metals / Jie Liu, Robert A. Goyer, and Michael P. Waalkes -- Toxic effects of solvents and vapors / James V. Bruckner, S. Satheesh Anand, and D. Alan Warren -- Health effects of radiation and radioactive materials / Naomi H. Harley -- Properties and toxicities of animal venoms / John B. Watkins, III -- Toxic effects of plants / Stata Norton -- Unit VI: Environmental toxicology -- Air pollution / Daniel L. Costa -- Ecotoxicology / Richard T. Di Giulio and Michael C. Newman -- Unit VII: Applications of toxicology -- Food toxicology / Frank N. Kotsonis and George A. Burdock -- Analytic/forensic toxicology / Alphonse Poklis -- Clinical toxicology / Louis R. Cantilena Jr. -- Occupational toxicology / Peter S. Thorne. "Long established as the gold standard in the field, Casarett & Doull's Toxicology equips you with an unsurpassed understanding of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. The new edition features many new contributors, new content on chemical terrorism, and is updated throughout."--Publisher description.