Record Display for the EPA National Library Catalog


Main Title Health assessment document for trichloroethylene : review draft /
Author Davidson, I. W. F. ; Greenberg, Mark M. ; Parker, Jean C.
Other Authors
Author Title of a Work
Parker, Jean C.
CORP Author Environmental Protection Agency, Research Triangle Park, NC. Environmental Criteria and Assessment Office.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Criteria and Assessment Office,
Year Published 1982
Report Number EPA-600/8-82-006
Stock Number PB83-135970
OCLC Number 20601543
Subjects Trichloroethylene
Additional Subjects Toxicology ; Industrial medicine ; Exposure ; Residues ; Humans ; Laboratory animals ; Teratogens ; Carcinogens ; Physiological effects ; Ethylene/trichloro ; Air pollution effects(Humans) ; Occupational safety and health ; Toxic substances
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  EPA-600/8-82-006 Region 1 Library/Boston,MA 05/25/2016
EJAD  EPA 600/8-82-006B Region 3 Library/Philadelphia, PA 10/29/1993 DISPERSAL
EJBD ARCHIVE EPA 600/8-82-006 Headquarters Library/Washington,DC 04/17/2009
EJED  EPA 600/8-82-006 OCSPP Chemical Library/Washington,DC 04/23/1999
ESAD  EPA 600-8-82-006 Region 10 Library/Seattle,WA 07/29/2005
NTIS  PB83-135970 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 volume (various pagings)
Exposure to trichloroethylene is associated with neurological disorders, cardiovascular effects and damage to the liver and kidney. Liver and kidney damage have been attributed to chronic high exposure (>1.000 ppm). It is highly likely that the direct myocardial depressent effect, which is a serious health hazard for those with compromised or reduced cardiac reserve, occurs at lower exposure concentrations than has been previously thought. Although animal teratology studies performed to date are inconclusive, trichloroethylene could be teratogenic since: (1) it is distributed in the fetus, (2) biotransformation into reactive metabolites occurs in fetal liver, and (3) trichloroethylene has high lipid solubility.
Includes bibliographical references. "EPA-600/8-82-006." "March 1982." "This document is a preliminary draft. It has not been formally released by EPA and should not at this stage be construed to represent Agency policy. It is being circulated for comment on its technical accuracy and policy implications."