Record Display for the EPA National Library Catalog


Main Title Dissecting the Molecular Anatomy of Tissue [electronic resource] /
Author Emmert-Buck, Michael R.
Other Authors
Author Title of a Work
Gillespie, John W.
Chuaqui, Rodrigo F.
Publisher Springer Berlin Heidelberg,
Year Published 2005
Call Number QH573-671
ISBN 9783540264828
Subjects Life sciences ; Oncology ; Immunology ; Human anatomy ; Biochemistry ; Cytology
Internet Access
Description Access URL
Collation XVIII, 230 p. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Clinkal Issues and Tissue Processing -- Molecular Pathology Laboratory of the Future -- Clinical Utilities of Microdissected Samples -- Tissue Processing -- Sample Management and Tracking -- Methods of Tissue Microanalysis -- Tissue Microarrays -- Molecular Analysis of Microdissected Samples -- Methods of Microdissection and New Technologies -- Standard Diagnostic Techniques -- DNA Applications -- mRNA Applications -- Proteomic Applications -- Protocols for Tissue Handling and Molecular Analysis. The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.