Record Display for the EPA National Library CatalogRECORD NUMBER: 3 OF 5
|Main Title||Biochemical changes in humans upon exposure to sulfuric acid aerosol and exercise /|
|Publisher||Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency,|
|Subjects||Sulfuric acid--Health aspects|
|Additional Subjects||Sulfuric acid ; Exercise(Physiology) ; Toxicology ; Aerosols ; Humans ; Exposure ; Biochemistry ; Blood ; Concentration(Composition) ; Physiological effects ; Glutathione ; Tocopherol ; Nitrogen organic compounds ; Phosphorus organic compounds ; Air pollution effects(Humans) ; Toxic substances ; Reductases/glutathione ; Aminotransferases/aspartate ; Diphosphoglyceric acid|
|Collation||iv, 19 p. ; 28 cm.|
A total of 18 human subjects were exposed to ambient air for four hours on the first day of exposure and to four hours of 100 micrograms/cu. m. (0.033 micromole) sulfuric acid aerosol exposed to four hours of ambient air on both exposure days. Six biochemical blood parameters were measured pre and post exposure: glutathione, lysozyme, glutathione reductase, serum glutamic oxaloacetic acid transaminase, serum vitamin E and 2,3-diphosphoglyceric acid. The results indicate no significant effect of one four hour exposure of humans to sulfuric acid aerosol (100 micrograms/cu. m.). One significant effect did occur indicating an increase in glutathione reductase post exposure for both the control group and acid group. This report covers a period from October 23, 1978, to December 15, 1978, and work was completed as of May 1, 1979.
"Clinical Pathology Branch, Clinical Studies Division, Health Effects Research Laboratory." "August 1979." Includes bibliographical references (p. 8-9). "EPA-600/1-79-032."