||Tumorigenesis by a Ferroactinolite Mineral.
Coffin, David L. ;
Palekar, Lalita D. ;
Cook, Philip M. ;
||Health Effects Research Lab., Research Triangle Park, NC.
Laboratory animals ;
Air pollution effects(Animals)
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
In lifetime exposure of male Fischer-344 rats to ferroactinolite fibers and to UICC amosite asbestos fibers by means of intratracheal and intrapleural treatments, oncogenesis was greater in the lung for the ferroactinolite and in the pleura for the amosite. The lack of correlation between the effects of the two methods of exposure suggests that in this instance, intrapleural inoculation was not a good predictor of pulmonary response on the basis of mass dose.