The U.S. EPA Office of Research and Development supported a waste minimization research program in 1986-1988 for small and medium sized generators to develop and promote the use of innovative technologies and management practices to reduce the generation of hazardous wastes. The program was established in response to the needs of small quantity hazardous waste generators in the areas of waste management, regulatory compliance, and waste reduction. Waste reduction is seen as one key way to help small businesses improve waste management by reducing liability, product costs, disposal costs, and environmental, health, and safety concerns. At the time, the program consisted of two efforts with the State of Minnesota and the Governmental Refuse Collection and Disposal Association (GRCDA). Results from these two cooperative research efforts are being used to assist small and medium sized businesses work toward waste reduction, improve waste management, and achieve regulatory compliance. Results from these two efforts are presented in the paper.